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Gut Instincts: How ADM is Leveraging the Microbiome to Boost Your Health

As consumers grow increasingly concerned with the potential adverse effects of pharmaceutical agents and turn towards natural health solutions, ADM Biopolis has been working for more than a decade on developing probiotic supplements that boost health and wellness by addressing the source of many chronic conditions: the gut microbiome. Here is a look at three innovative probiotic solutions designed by ADM Biopolis that bring a natural yet effective approach to health.


Psoriasis is a very common skin condition affecting 2 – 5% of the global population and is characterized by red, scaly patches on the skin. For mild-to-moderate psoriasis, the mainstay of treatment is the topical application of corticosteroids. Although the potency of these ointments and gels vary, stronger corticosteroids have been shown to inflict skin damage through repeated long-term use. Tougher treatment options, including the use of systemic antibody therapy, are associated with serious side effects. Beyond the physical symptoms, the impact of disfiguring skin lesions have psychosocial consequences for patients, reducing the quality of life for millions.

In a recent clinical trial spearheaded by ADM Biopolis, patients with mild-to-moderate psoriasis being treated with corticosteroids responded to a probiotic blend comprising two strains of bifidobacteria and a strain of lactobacillus, with a marked trend for reduction in the severity of the psoriatic skin lesions and showed lower rates of relapse 6 months after the completion of the study, compared to the placebo group that received only the corticosteroids. The potential for the probiotic to improve the effectiveness of standard pharmacological treatment positions it as an original and natural approach to psoriasis.

Metabolic disorders

In developed nations, obesity has already reached pandemic levels, resulting in alarming rates of cardiovascular and metabolic disorders, with rising concerns in developing countries. Interestingly, among several contributing factors, our gut bacteria are known to affect how our bodies metabolize the food that we eat and convert it into energy, making the gut a natural target in regulating our weight and preventing related disorders.

In 2018, ADM Biopolis evaluated the effect of both a live and heat-treated version of the probiotic strain Bifidobacterium lactis BPL1 in a randomized, double-blind, placebo-controlled clinical trial involving 135 abdominally obese individuals. After three months of consuming the probiotic in either form, the individuals showed an improvement in markers of obesity, including body mass index, and risk factors for cardiovascular disease compared to the placebo group, supporting the use of the probiotic as a complementary approach in managing obesity.


Infertility affects 15% of couples. About 40% of these cases appear to be caused by male factor infertility, including a condition characterized by reduced or absent sperm motility, known as asthenozoospermia, which affects 1 in 5000 men. Although medical treatments have improved the chances for these couples to have children, probiotic supplementation to improve sperm motility remains an unexplored avenue to boost fertility naturally.

In a 2017 study, the quality of sperm samples taken from a group of men with asthenozoospermia showed significant improvements after three and six weeks of consuming ADM’s probiotic mixture consisting of two strains of Lactobacillus rhamnosus and Bifidobacterium longum. Sperm motility was considerably enhanced and the sperm cells themselves showed far less DNA damage. These preliminary results pave the way for probiotics to gain greater traction as part of natural therapies addressing male infertility, which can be used before attempting assisted reproductive techniques or even natural reproduction.

Learn more about these and other offerings at http://biopolis.es/.